OpenSource Antibiotics
I just thought I’d highlight a new project I’m involved with.
Open Source Antibiotics (https://github.com/opensourceantibiotics) is intended to be a platform for a collaborative effort towards antibiotic discovery.
The first projects have been initiated
Mur Ligase (https://github.com/opensourceantibiotics/murligase) and the background to these exciting targets can be found on the wiki page.
https://github.com/opensourceantibiotics/murligase/wiki
This also provides details of the first two fragment screens.
MurD https://github.com/opensourceantibiotics/murligase/wiki/MurD-fragment-screen
and
MurE https://github.com/opensourceantibiotics/murligase/wiki/MurE-fragment-screen
What we want now is for people to join in and suggest the next round of fragments that should be screened. Ideally these should be commercially available but if people want to design, make and submit their own fragments we would be happy to screen them.
If you feel appropriate, we would appreciate any publicity on this exciting new project